Ismert vagy gyanított vesebetegség esetén a vesefunkció megítélésére használható, de csak olyan esetekben, amikor a hagyományos vesefunkciós vizsgálatok eredménye félrevezető lehet.
Ha kezelőorvosa arra gyanakszik, hogy önnek vesefunkciózavara van, de a szérum kreatininszint mérés eredménye nem megbízható. Ismert vesebetegség esetén rendszeres időközönként kérhetik a vizsgálatot.
A kar egy könyökhajlati vénájából vett vérmintára.
A vizsgálat nem igényel különleges előkészületet.
Aktuális áttekintésben használt források
2017 review performed by Joshua E Raizman, PhD, FCACB.
Ebert N, Delanaye P, Shlipak M, Jakob O, Martus P, Bartel J, Gaedeke J, van der Giet M, Schuchardt M, Cavalier E, Schaeffner E. Cystatin C standardization decreases assay variation and improves assessment of glomerular filtration rate. Clin Chim Acta. 2016 May 1;456:115-21.
Kidney Disease Improving Global Outcomes, KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Available online at http://www.kdigo.org/clinical_practice_guidelines/pdf/CKD/KDIGO_2012_CKD_GL.pdf. Accessed April 2017.
Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, Kusek JW, Manzi J, Van Lente F, Zhang YL, Coresh J, Levey AS.; CKD-EPI Investigators Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012 Jul 5;367(1):20-9.
Waheed S, Matsushita K, Sang Y, Hoogeveen R, Ballantyne C, Coresh J, Astor BC. Combined association of albuminuria and cystatin C-based estimated GFR with mortality, coronary heart disease, and heart failure outcomes: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis. 2012 Aug;60(2):207-16.
Dalcomune DM, Terrão J, Porto ML, Vasquez EC, Baldo MP, Pereira TM. Predictive value of cystatin C for the identification of illness severity in adult patients in a mixed intensive care unit. Clin Biochem. 2016 Jul;49(10-11):762-7.
Brown CS, Kashani KB, Clain JM, Frazee EN. Cystatin C Falsely Underestimated GFR in a Critically Ill Patient with a New Diagnosis of AIDS. Case Rep Nephrol. 2016;2016:9349280.
©2014 National Kidney Foundation. Frequently asked questions about GFR estimates. Available online at https://www.kidney.org/sites/default/files/docs/12-10-4004_abe_faqs_aboutgfrrev1b_singleb.pdf. Accessed 26/04/2017.
Korábbi áttekintések során használt források
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