A vizsgálat vérzékenységgel vagy vérrög képződéssel (trombotikus esemény) járó betegségek kivizsgálásának részeként; ismétlődő vetélések okát feltáró kivizsgálásban vagy az antifoszfolipid szindróma diagnózisának felállításában; ha szükséges, a nem frakcionált (hagyományos) heparin alvadásgátló terápia monitorozására; illetve sebészeti vagy más invazív beavatkozás előtt az alvadási szűrővizsgálatok részeként is alkalmazható.
Amennyiben a betegnek tisztázatlan vérzéses panaszai, kóros véralvadási eredményei vannak vagy ismétlődő vetélések szerepelnek a kórelőzményben; olykor alkalmazzák hagyományos (nem frakcionált) heparin alvadásgátló terápia monitorozásában; néha tervezett sebészeti beavatkozások előtt.
Vérminta szükséges a vizsgálathoz, melyet a páciens karjának könyökhajlati vénájából vesznek tűvel.
A vizsgálathoz előkészület nem szükséges; azonban a vérvételt megelőzően fogyasztott nagyon zsíros étel zavarhatja a vizsgálatot, ezért célszerű éhgyomorra vagy könnyű étkezést követően érkezni a vérvételre.
Aktuális áttekintésben használt források
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(November 23, 2015) Partial Thromboplastin Time, Activated. Medscape. Available online at https://emedicine.medscape.com/article/2085837-overview. Accessed March 2019.
(June 2013) Elevated APTT? How to Best Follow Up. Journal of Family Practice. Available online at https://www.mdedge.com/jfponline/article/76289/cardiology/elevated-aptt-how-best-follow. Accessed March 2019.
Partial Thromboplastin Time (PTT). MedlinePlus. Available online at https://medlineplus.gov/ency/article/003653.htm. Accessed March 2019.
Activated Partial Thromboplastin Time (APTT). University of Rochester Medical Center. Available online at https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=aptt. Accessed March 2019.
Vandiver JW, Vondracek T. Antifactor Xa levels versus activated partial thromboplastin time for monitoring unfractionated heparin. Pharmacotherapy. 2012 Jun;32(6):546-58. Available online at https://www.ncbi.nlm.nih.gov/pubmed/22531940. Accessed March 2019.
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Tests
Conditions
https://www.hematology.org/education/patients/blood-clots
https://www.hematology.org/education/patients/bleeding-disorders
https://www.hemophilia.org/bleeding-disorders-a-z
https://medlineplus.gov/bleedingdisorders.html
https://www.mayoclinic.org/symptoms/blood-clots/basics/definition/sym-20050850
https://www.mayoclinic.org/diseases-conditions/hemophilia/symptoms-causes/syc-2…