A gesztációs trofoblasztikus betegség (GTD) vagy csírasejtdaganatok diagnosztizálásának és monitorozásának elősegítésére.
Amikor a tünetek gesztációs trofoblasztikus betegségre vagy csírasejtdaganatokra utalnak; ezen állapotokban a kezelés hatékonyságának megítélésére; a kiújulás monitorozására.
A kar egyik könyökhajlati vénájából vett vérmintára.
A vizsgálat nem igényel speciális előkészületet.
Aktuális áttekintésben használt források
2018 review performed by Kristin Hauff, PhD, FCACB, Interior Health Laboratories BC.
Sisinni L., Landriscina M. (2015) The Role of Human Chorionic Gonadotropin as Tumor Marker: Biochemical and Clinical Aspects. In: Scatena R. (eds) Advances in Cancer Biomarkers. Advances in Experimental Medicine and Biology, vol 867. Springer, Dordrecht.
Nwabuobi C, et al. (2017) hCG: Biological Functions and Clinical Applications. International Journal of Molecular Science. 18(10) pii: E2037. Available online at https://www.mdpi.com/1422-0067/18/10/2037/htm. Accessed October 2018.
Stenman U., Alfthan H. (2013) Determination of human chorionic gonadotropin. Best Practice & Research Clinical Endocrinology & Metabolism. 27(6); 783-793.
Sokoll L.J., Rai A.J., and Chan D.W. (2012) Tumor Markers. In: Burtis C.A, Ashwood E.R and Burns D.E. (eds) Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 5th edition Elsevier, St. Louis, Missouri.
Braustein GD, Buster JE, Soares JR and Gross SJ (1983). Pregnancy hormone concentrations in marijuana users. Life Science 33(2): 195-9.
Braustein GD, Thompson R, Gross SJ and Soares JR (1983). Marijuana use does not spuriously elevate serum human chorionic gonatotropin levels. Urology 25(6): 605-6.
Montagnana M., et al. (2011) Human chorionic gonadotropin in pregnancy diagnostics. Clinica Chimica Acta 412(17): 1515-1520. Available online at http://www.bccancer.bc.ca/health-professionals/clinical-resources/cancer-management-guidelines/gynecology/gestational-trophoblastic-neoplasia#Diagnosis-Gestational-Trophoblastic-Neoplasia. Accessed October 2018.
Korábbi áttekintések során használt források
Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.
(2004). Germ Cell Tumors: Beta-Human Chorionic Gonadotropin. Specialty Laboratories, Use and Interpretation of Laboratory Tests, Books [On-line information]. Available online at http://oncology.specialtylabs.com/books/display.asp?id=544.
American Cancer Society. What is gestational trophoblastic disease? Available online at http://www.cancer.org/Cancer/GestationalTrophoblasticDisease/DetailedGuide/gestational-trophoblastic-disease-what-is-g-t-d. Accessed March 2011.
MedlinePlus Medical Encyclopedia. Gestational Trophoblastic Disease. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/007333.htm. Accessed March 2011.
Enrique Hernandez, MD, FACOG, FACS. Gestational Trophoblastic Neoplasia. Available online at http://emedicine.medscape.com/article/279116-overview. Accessed March 2011.
Farinde, A. (Updated 2014 July 2). Human Chorionic Gonadotropin (hCG). Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2089158-overview. Accessed September 2014.
(Revised 2014 March 3). Gestational Trophoblastic Disease. American Cancer Society [On-line information]. Available online at http://www.cancer.org/acs/groups/cid/documents/webcontent/003104-pdf.pdf. Accessed September 2014.
(Revised 2013 October 30). Tumor Markers. American Cancer Society [On-line information]. Available online at http://www.cancer.org/acs/groups/cid/documents/webcontent/003189-pdf.pdf. Accessed September 2014.
(Modified 2014 April 25). General Information About Gestational Trophoblastic Disease. National Cancer Institute [On-line information]. Available online at http://www.cancer.gov/cancertopics/pdq/treatment/gestationaltrophoblastic/HealthProfessional. Accessed September 2014.
(Modified 2014 July 11). General Information About Testicular Cancer. National Cancer Institute [On-line information]. Available online at http://www.cancer.gov/cancertopics/pdq/treatment/testicular/HealthProfessional. Accessed September 2014.
Zhang, Y. (2013 March 13). Tumor Markers: Alpha-fetoprotein (AFP) and human Chorionic Gonadotropin (hCG). Clinical Chemistry Trainee Council Pearls of Laboratory Medicine [On-line information]. Available online through http://www.aacc.org. Accessed September 2014.
Hussain, F. et. al. (Updated 2012 August 1). Gynecologic Tumor Markers Tumor Marker Overview. Medscape Drugs & Diseases http://emedicine.medscape.com/article/269839-overview. Accessed September 2014.
Storck, S. (Updated 2012 November 8). Hydatidiform mole. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000909.htm. Accessed September 2014.
Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 558-560.
Sturgeon C, et. al. National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. Clin Chem 2008; 54(12):e11-79. Available online through http://www.aacc.org. Accessed October 2014.
United States Anti-Doping Agency. Effects of Performance Enhancing Drugs. Available online at http://www.usada.org/substances/effects-of-performance-enhancing-drugs/. Accessed October 2014.
Quest Diagnostics. Bet-HCG, serum quant tumor marker. Available online at http://www.questdiagnostics.com/testcenter/BUOrderInfo.action?tc=20862&labCode=QER. Accessed October 2014.
Medscape. Beta human chorionic gonadotropin. Available online at http://emedicine.medscape.com/article/269839-overview#aw2aab6b4. Accessed October 2014.
Tests
AFP (Alfa-fötoprotein) tumor marker
Conditions
https://medlineplus.gov/ency/article/007333.htm
https://www.cancer.org/cancer/gestational-trophoblastic-disease/about/what-is-g…
https://www.cancer.org/cancer/ovarian-cancer/detection-diagnosis-staging/detect…
https://www.cancer.org/cancer/testicular-cancer/detection-diagnosis-staging/how…
https://www.cancer.gov/types/gestational-trophoblastic/patient/gtd-treatment-pd…
https://www.cancer.gov/types/testicular/patient/testicular-treatment-pdq?redire…